Serveur d'exploration sur la grippe en Espagne

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[Variability in the reporting of adverse reactions to the pandemic and seasonal influenza vaccine: seasons 2009-2010 and 2010-2011. Valencian community, Spain].

Identifieur interne : 000277 ( Main/Exploration ); précédent : 000276; suivant : 000278

[Variability in the reporting of adverse reactions to the pandemic and seasonal influenza vaccine: seasons 2009-2010 and 2010-2011. Valencian community, Spain].

Auteurs : Ana María Alguacil Ramos [Espagne] ; José Antonio Lluch Rodrigo ; Antonio Portero Alonso ; Rosa Martín Ivorra ; Eliseo Pastor Villalba

Source :

RBID : pubmed:22991081

Descripteurs français

English descriptors

Abstract

BACKGROUND

The loss of confidence in the safety of vaccines derived from alarm conditions, as in the case of the flu pandemic may affect both vaccination coverage and the sensitivity to the reporting of suspected adverse reactions associated vaccines (SRAAV). The aim of the study is to describe the adverse effects reported to the vaccine against pandemic influenza in the 2009-2010 season and against seasonal influenza in 2009-2010 and 2010-2011 seasons, by type of vaccine, risk groups and by age group in the Valencian Community (CV).

METHODS

A retrospective descriptive study has been made of the individuals presenting suspected adverse reactions to the influenza vaccine reported through the Vaccine Information System during the seasons 2009-2010 and 2010-2011 in the Valencian Community. 95% confidence intervals were calculated.

RESULTS

During the period 2009-2010 the reporting rate of suspected reactions for seasonal influenza vaccine was 0.020 per thousand doses administered, for the pandemic vaccine 0.95. The reporting rate for seasonal influenza vaccine in the period 2010-2011 was 0.04 per thousand.

CONCLUSIONS

There was an increase in the number of reported suspected adverse reactions to the pandemic vaccines compared with the rest of influenza vaccines, during the seasons. The highest suspected adverse reaction reporting rate was for the group of health professionals partner for both vaccines against seasonal and pandemic influenza.


DOI: 10.1590/S1135-57272012000300004
PubMed: 22991081


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Adolescent (MeSH)</term>
<term>Adult (MeSH)</term>
<term>Adverse Drug Reaction Reporting Systems (statistics & numerical data)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Child (MeSH)</term>
<term>Child, Preschool (MeSH)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
<term>Influenza A Virus, H1N1 Subtype (immunology)</term>
<term>Influenza Vaccines (adverse effects)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (prevention & control)</term>
<term>Male (MeSH)</term>
<term>Mass Vaccination (adverse effects)</term>
<term>Mass Vaccination (statistics & numerical data)</term>
<term>Middle Aged (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Retrospective Studies (MeSH)</term>
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<term>Young Adult (MeSH)</term>
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<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
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<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Espagne (épidémiologie)</term>
<term>Femelle (MeSH)</term>
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<term>Vaccination de masse (effets indésirables)</term>
<term>Vaccination de masse (statistiques et données numériques)</term>
<term>Vaccins antigrippaux (effets indésirables)</term>
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<term>Influenza Vaccines</term>
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<term>Adverse Drug Reaction Reporting Systems</term>
<term>Mass Vaccination</term>
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<term>Systèmes de signalement des effets indésirables des médicaments</term>
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<term>Humans</term>
<term>Infant</term>
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<term>Middle Aged</term>
<term>Pandemics</term>
<term>Retrospective Studies</term>
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<term>Young Adult</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
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<div type="abstract" xml:lang="en">
<p>
<b>BACKGROUND</b>
</p>
<p>The loss of confidence in the safety of vaccines derived from alarm conditions, as in the case of the flu pandemic may affect both vaccination coverage and the sensitivity to the reporting of suspected adverse reactions associated vaccines (SRAAV). The aim of the study is to describe the adverse effects reported to the vaccine against pandemic influenza in the 2009-2010 season and against seasonal influenza in 2009-2010 and 2010-2011 seasons, by type of vaccine, risk groups and by age group in the Valencian Community (CV).</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>A retrospective descriptive study has been made of the individuals presenting suspected adverse reactions to the influenza vaccine reported through the Vaccine Information System during the seasons 2009-2010 and 2010-2011 in the Valencian Community. 95% confidence intervals were calculated.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>During the period 2009-2010 the reporting rate of suspected reactions for seasonal influenza vaccine was 0.020 per thousand doses administered, for the pandemic vaccine 0.95. The reporting rate for seasonal influenza vaccine in the period 2010-2011 was 0.04 per thousand.</p>
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<b>CONCLUSIONS</b>
</p>
<p>There was an increase in the number of reported suspected adverse reactions to the pandemic vaccines compared with the rest of influenza vaccines, during the seasons. The highest suspected adverse reaction reporting rate was for the group of health professionals partner for both vaccines against seasonal and pandemic influenza.</p>
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